: A second booster? It’s time scientists shift focus to vaccines with long-lived antibody response #IndiaNEWS With yet another Covid-19 booster available for vulnerable populations in the United States,

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A second booster? It’s time scientists shift focus to vaccines with long-lived antibody response #IndiaNEWS
With yet another Covid-19 booster available for vulnerable populations in the United States, many people find themselves wondering what the end game will be.The mRNA vaccines currently used in the US against Covid-19 have been highly successful at preventing hospitalisation and death. The Commonwealth Fund recently reported that in the US alone, the vaccines have prevented over 20 lakh people from dying and over 1.7 crore from hospitalisation.However, the vaccines have failed to provide long-term protective immunity to prevent breakthrough infections – cases of Covid-19 infection that occur in people who are fully vaccinated.Because of this, the Centers for Disease Control and Prevention recently endorsed a second booster shot for individuals 50 years of age and older and people who are immunocompromised. Other countries including Israel, the United Kingdom and South Korea have also approved a second booster.However, it has become increasingly clear that the second booster does not provide long-lasting protection against breakthrough infections. As a result, it will be necessary to retool the existing vaccines to increase the duration of protection in order to help bring the pandemic to an end.As immunologists studying the immune response to infections and other threats, we are trying to better understand the vaccine booster-induced immunity against Covid-19.Longer-term immunityIt is a bit of a medical mystery: why are mRNA vaccines so successful in preventing the serious form of...Read more

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